Circadian Health Glossary
Phase Response Curve (PRC)
A Phase Response Curve (PRC) describes the relationship between a stimulus, such as light exposure, and its effect on shifting the body’s circadian rhythm (phase shift). It illustrates how the timing of the stimulus determines whether it causes a phase delay or phase advance in the circadian cycle.
How Does the PRC Work?
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Light Exposure Before Minima: Causes a phase delay, making the body’s internal clock run later.
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Light Exposure After Minima: Leads to a phase advance, shifting the circadian rhythm earlier.
Why Is the PRC Important?
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Personalized Light Therapy: Helps determine the best timing for light exposure to achieve desired circadian shifts.
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Circadian Health Management: Guides treatments for sleep disorders, jet lag, and shift work misalignment.
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Scientific Research: PRCs are foundational tools for understanding the effects of external stimuli on the biological clock.