Circadian Health for everyone

Our approach combines Chronobiology & Light Therapy with latest tech and collaboration with leading scientists around the world.

SUPPORTED BY SCIENCE AND CLINICAL RESEARCH

Numerous clinical studies and over 20 years of Chronobiology and Light Therapy research performed in leading institutions, including Harvard, Oxford and NASA, have shown that we can actively support our circadian rhythm in order to obtain healthier, happier and more active lives. These disciplines and insights are the cornerstone of Circadian Health.

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The Science Behind AYO (1:26)

Chronobiology

Chronobiology is the study of biological rhythms, variations of the timing and duration of biological activity in living organisms. At the center of chronobiology research is the circadian rhythm and the human 24-hour circadian clock located in the suprachiasmatic nucleus (SCN) in the brain. This biological clock controls most of the brain and body functions including sleep, energy, mood, performance, metabolism, and the immune system. AYO is working on translating chronobiology clinical research into practical applications.

Light Therapy

Light therapy, also known as phototherapy, is a treatment in which you’re exposed to a special artificial light source. While it might sound like a wellness fad, it is a widely-used and recognized method backed by thousands of peer-reviewed articles and studies. The clinical consensus is that blue light treatment is generally safe and effective in resetting the human circadian rhythm with numerous health benefits. AYO is an innovation leader in personalized blue light therapy.

RESEARCH-FOCUSED

Clinically-backed health and wellness benefits

AYO is a science-based company advised by some of the world’s leading experts and researchers like Prof. Dr. Thomas Kantermann. As pioneers in the novel field called Circadian Health, we are helping reshape the foundation of health and wellness. We are committed to working with research and clinical partners and are actively collaborating on clinical studies.

 

AYO is taking part in over 10 scientific studies and two have been already 2 published, showing AYO to help improve sleep quality, reduce sleep problems and improve performance.

HOW IT WORKS

Holistic approach utilizing your own biology and light

Light stimulates specialized cells in your eyes
AYO makes it easy for you to get properly timed good light. This nurtures a natural mechanism in your body essential in supporting your circadian rhythm.

Like sunlight, AYO’s gentle blue light enters your eyes and stimulates sensory cells in the retina called photosensitive Retinal Ganglion Cells (ipRGCs). This sends a biological signal through the optic nerve towards your body’s master clock located in your brain.
Robust circadian clock promotes better body function
The human body functions based on finely synchronized biological processes. AYO’s light signal helps fine-tune your master clock, known as suprachiasmatic nucleus (SCN).

This timekeeping controller is crucial in managing all the other clocks found in almost every organ of your body (e.g. your heart or liver have their own clocks). AYO promotes better light-timed cellular management of your body through these biological mechanisms including the circadian PER protein.
Aligning your natural & lifestyle rhythm for a better you
Your sleep, heart rate and blood pressure, immune system, metabolism, body temperature, hormones, performance and mood, are all influenced by your circadian rhythm.

AYO helps you align this natural cycle of physical, mental, and behaviour changes that the body goes through during 24-hours, with your lifestyle rhythm and daily activities. By getting your rhythms in sync, you can enjoy a myriad of health & wellness benefits.

Light stimulates specialized cells in your eyes

AYO makes it easy for you to get properly timed good light. This nurtures a natural mechanism in your body essential in supporting your circadian rhythm.

Like sunlight, AYO’s gentle blue light enters your eyes and stimulates sensory cells in the retina called photosensitive Retinal Ganglion Cells (ipRGCs). This sends a biological signal through the optic nerve towards your body’s master clock located in your brain.

Robust circadian clock promotes better body function

The human body functions based on finely synchronized biological processes. AYO’s light signal helps fine-tune your master clock, known as suprachiasmatic nucleus (SCN).

This timekeeping controller is crucial in managing all the other clocks found in almost every organ of your body (e.g. your heart or liver have their own clocks). AYO promotes better light-timed cellular management of your body through these biological mechanisms including the circadian PER protein.

Aligning your natural & lifestyle rhythm for a better you

Your sleep, heart rate and blood pressure, immune system, metabolism, body temperature, hormones, performance and mood, are all influenced by your circadian rhythm.

AYO helps you align this natural cycle of physical, mental, and behaviour changes that the body goes through during 24-hours, with your lifestyle rhythm and daily activities. By getting your rhythms in sync, you can enjoy a myriad of health & wellness benefits.

WHAT SCIENCE SAYS

Revolutionizing health and wellness

“AYO's approach to Circadian Health is essential for keeping our circadian rhythms in synchrony with the 24-hour day & night cycle.”

The human body functions based on finely synchronized biological processes. Desynchronization between social and biological time constitute a regular challenge for many people nowadays. As a result, serious consequences for sleep, wellbeing and health can follow. Daily provision of timed light and dark exposure with additional “time cues” to the circadian rhythm will help maintain restorative sleep, wellbeing and health.”

Prof. Dr. Thomas Kantermann

Chief Scientific Officer, AYO

“AYO's approach to Circadian Health is essential for keeping our circadian rhythms in synchrony with the 24-hour day & night cycle

The human body functions based on finely synchronized biological processes. Desynchronization between social and biological time constitute a regular challenge for many people nowadays. As a result, serious consequences for sleep, wellbeing and health can follow. Daily provision of timed light and dark exposure with additional “time cues” to the circadian rhythm will help maintain restorative sleep, wellbeing and health.”

Prof. Dr. Thomas Kantermann

Chief Scientific Officer, AYO

Key to a healthier, happier and more active life

Circadian Health

Good

Good Circadian Health

Being in sync with your natural rhythm by aligning your lifestyle and your internal clock pays out greatly and results in good Circadian Health. A robust and entrained circadian rhythm can promote deep restorative sleep, better metabolism, improved performance, higher levels of energy, better mood, longevity and overall feeling of improved health and wellbeing. There are over 500 studies linking circadian rhythm and light to various health and wellness benefits.

Good Circadian Health

Being in sync with your natural rhythm by aligning your lifestyle and your internal clock pays out greatly and results in good Circadian Health. A robust and entrained circadian rhythm can promote deep restorative sleep, better metabolism, improved performance, higher levels of energy, better mood, longevity and overall feeling of improved health and wellbeing. There are over 500 studies linking circadian rhythm and light to various health and wellness benefits.

Poor Circadian Health

Being out of sync with your natural rhythm due to ever-increasing differences between your internal clock and lifestyle results in poor Circadian Health. This can have significant health & wellness consequences, including chronic problems like higher risk of obesity, heart disease, diabetes, depression, certain type of cancers, gut disorders, infections, allergies and premature aging. There are hundreds of studies linking circadian disruption with poor health and wellness.

EFFICIENT AND EFFECTIVE

The Best Circadian Tech has to offer

Full package

Circadian Health requires deep understanding of your natural rhythm and properly timed light exposure. AYO brings these two ingredients conveniently together providing you with an unparalleled experience. The wearable provides you with the optimal light session timing and duration, while the app delivers you all the guidance and chronometrics you need.

Circadian effective light

Not all light is made equal and AYO is the best example of this. We utilize a special narrow-band blue light within 470nm frequency and irradiance of 150 qW/cm2. These light properties have been shown to be the most effective and efficient in optimizing the human circadian rhythm.

Deep understanding of your natural rhythm

Light is only one half of the circadian health equation. AYO provides you with a deep understanding of your circadian rhythm including your chronotype and key chronometrics. These highly personal insights paired with actionable advice, allow you to use your own biology to achieve your health and wellness goals.

WHAT EXPERTS SAY

Quality, Ingenuity and Effectiveness

AYO is the first step in the personal adjustments of internal body clocks. It will help us to improve our lifestyle, to remain healthy, and to keep the doctor away.
Prof. Bert van der Horst
Chairman of Health and Chronobiology, Erasmus Medical Center, The Netherlands
Our brain’s response to day and night cycles has an impact on our readiness to perform. With AYO, we are looking to protect health, athlete development, and advancing human performance.
Dr. John P. Sullivan
Sport Scientist, Clinical Sport Psychologist, Founder of Clinical & Sports Consulting Services, United States
Best looking and highest tech/most ingenious light therapy glasses I’ve seen yet
Kimberly E. Erway, M.D.
Medical Director, Behavioral Health, Excellus Blue Cross Blue Shield, United States
Circadian disruption was ever present prior to the pandemic. Now, as the world goes back to a more normal schedule, people need more help than ever getting their circadian rhythms and sleep into a healthy place. Intelligent use of devices like AYO are my secret to helping my patients and athletes quickly get their sleep rhythms in order.

W. Christopher Winter, MD
Sleep Specialist/Neurologist & Author of The Rested Child and The Sleep Solution, United States
For the last decade my colleagues and I at the Mount Sinai Light and Health Research Center have been studying the systematic use of light exposure to treat fatigue, depression, and sleep problems in cancer patients and survivors. After testing several light delivery devices, we have found that AYO is by far the most reliable and easiest to use.

William H. Redd, PhD
Icahn Medical School at Mount Sinai, United States

Proven Technology

Safe & Natural

Certified Technology

AYO complies with United States of America’s FCC marking, European Union’s CE marking as well as other national and international regulatory directives.

Safe for the Eyes

UV and Infrared free, AYO is considered safe for the eyes in accordance with international standards and is independently certified by TÜV Rheinland.

Natural Solution

AYO is a general wellness device that utilizes completely natural mechanisms to improve your health & wellness. It is non-invasive and 100% drug free.

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